The BRMS1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Bovine, and Non-Human Primate antigen. The BRMS1 Antibody has been validated for the following applications: Immunoprecipitation, and Western Blot.
Description
BRMS1 is a transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis